Associations between brain structure and sleep patterns across adolescent development.

ABSTRACT:

Study objectives

Structural brain maturation and sleep are complex processes that exhibit significant changes over adolescence and are linked to many physical and mental health outcomes. We investigated whether sleep-gray matter relationships are developmentally invariant (i.e. stable across age) or developmentally specific (i.e. only present during discrete time windows) from late childhood through young adulthood.

Methods

We constructed the Neuroimaging and Pediatric Sleep Databank from eight research studies conducted at the University of Pittsburgh (2009-2020). Participants completed a T1-weighted structural MRI scan (sMRI) and 5-7 days of wrist actigraphy to assess naturalistic sleep. The final analytic sample consisted of 225 participants without current psychiatric di

SUBMITTER: Jalbrzikowski M 

PROVIDER: S-EPMC8503824 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature