Odd-Even Effect in Peptide SAMs-Competition of Secondary Structure and Molecule-Substrate Interaction.

ABSTRACT: Peptide-based self-assembled monolayers (SAMs) are well known to be crucial for biocompatible surface formation on inorganic substrates applied for implants, biosensors, or tissue engineering. Moreover, recently these bioinspired nanostructures are also considered particularly interesting for molecular electronics applications due to their surprisingly high conductance and thickness-independent capacitance, which make them a very promising element of organic field-effect transistors (OFETs). Our structural analysis conducted for a series of prototypic homooligopeptides based on glycine (Gly) with cysteine (Cys) as a substrate bonding group chemisorbed on Au and Ag metal substrates (Gly_nCys/Au(Ag), n = 1-9) exhibits the formation by these monolayers secondary struct

SUBMITTER: Grabarek A 

PROVIDER: S-EPMC8503877 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature