The diagnostic indicators of gestational diabetes mellitus from second trimester to birth: a systematic review.

ABSTRACT:

Background

Gestational diabetes mellitus (GDM) is glucose intolerance first recognised during pregnancy. Both modalities and thresholds of the GDM diagnostic test, the Oral Glucose Tolerance Test (OGTT), have varied widely over time and among countries. Additionally, OGTT limitations include inconsistency, poor patient tolerability, and questionable diagnostic reliability. Many biological parameters have been reported to be modified by GDM and could potentially be used as diagnostic indicators. This study aimed to 1) systematically explore biomarkers reported in the literature as differentiating GDM from healthy pregnancies 2) screen those indicators assessed against OGTT to propose OGTT alternatives.

Main body

A systematic review of GDM diagnostic indicators was performed a

SUBMITTER: Di Filippo D 

PROVIDER: S-EPMC8504031 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature