Intravitreal corticosteroids for diabetic macular edema: a network meta-analysis of randomized controlled trials.

ABSTRACT:

Background

To evaluate the efficacy and safety of different intravitreal corticosteroids for treating diabetic macular edema (DME).

Methods

Four databases were systematically searched for randomized controlled trials comparing different intravitreal corticosteroids for treating DME. The primary outcome was the change in best-corrected visual acuity (BCVA) within 6 months after the first injection (short-term BCVA). Secondary outcomes were the change in BCVA over 1 year (long-term BCVA) and changes in central macular thickness (CMT) and intraocular pressure (IOP) within 6 months after the first injection. Network meta-analysis was performed to aggregate the results from the individual studies.

Results

Nineteen trials involving 2839 eyes were included. Intravitreal tria

SUBMITTER: Gao L 

PROVIDER: S-EPMC8504110 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature