Is there a role for physical activity when treating patients with cancer with immune checkpoint inhibitors? Protocol for a scoping review.

ABSTRACT:

Introduction

For patients with cancer, immune checkpoint inhibitors (ICIs) produce superior long-term responses compared with alternative treatments, although at the cost of manifesting adverse immune-related events. There are many hypotheses of the impacts of physical activities in immunotherapy, but little is known about the oncological outcomes and the underlying mechanisms. This scoping review aims to identify possible physical activity interventions, their efficacy and feasibility and the potential underlying biological mechanisms responsible for their effects.

Method and analysis

The Levac methodology framework was used along with guidance from the Joanna Briggs Institute Manual for Evidence Synthesis to inform development of this protocol. Abstracts and titles followe

SUBMITTER: Chen M 

PROVIDER: S-EPMC8504359 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature