Lesion-induced changes of brevican expression in the perineuronal net of the superior vestibular nucleus.

ABSTRACT: Damage to the vestibular sense organs evokes static and dynamic deficits in the eye movements, posture and vegetative functions. After a shorter or longer period of time, the vestibular function is partially or completely restored via a series of processes such as modification in the efficacy of synaptic inputs. As the plasticity of adult central nervous system is associated with the alteration of extracellular matrix, including its condensed form, the perineuronal net, we studied the changes of brevican expression in the perineuronal nets of the superior vestibular nucleus after unilateral labyrinth lesion. Our results demonstrated that the unilateral labyrinth lesion and subsequent compensation are accompanied by the changing of brevican staining pattern in the perineuronal nets of super

SUBMITTER: Magyar A 

PROVIDER: S-EPMC8504393 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature