Rapid antiretroviral therapy initiation and its effect on treatment response in MSM in West Africa.

ABSTRACT:

Objective

To assess the time from HIV diagnosis to ART initiation and the effect of rapid ART initiation (i.e. within 7 days of HIV diagnosis) on attrition and virologic and immunologic responses among MSM in Burkina Faso, Côte d'Ivoire, Mali, and Togo.

Design

Prospective cohort study between 2015 and 2019.

Methods

MSM aged 18 years or older newly diagnosed with HIV infection were eligible to participate. ART was proposed to participants upon HIV diagnosis, irrespective of clinical stage and CD4+ cell count, and was initiated as soon as possible, with no specific time frame. Determinants of rapid ART initiation and its effect on treatment outcomes were assessed using multivariate analyses.

Results

Of 350 MSM, 335 (95.7%) initiated ART after a median time of 5 d

SUBMITTER: Dah TTE 

PROVIDER: S-EPMC8505135 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature