Left ventricular activation time and pattern are preserved with both selective and nonselective His bundle pacing.

ABSTRACT:

Background

His bundle pacing (HBP) can be achieved in 2 ways: selective HBP (S-HBP), where the His bundle is captured alone, and nonselective HBP (NS-HBP), where local myocardium is also captured, resulting a pre-excited electrocardiogram appearance.

Objective

We assessed the impact of this ventricular pre-excitation on left and right ventricular dyssynchrony.

Methods

We recruited patients who displayed both S-HBP and NS-HBP. We performed noninvasive epicardial electrical mapping for left and right ventricular activation time (LVAT and RVAT) and pattern.

Results

Twenty patients were recruited. In the primary analysis, the mean within-patient change in LVAT from S-HBP to NS-HBP was -5.5 ms (95% confidence interval: -0.6 to -10.4, noninferiority P < .0001)

SUBMITTER: Arnold AD 

PROVIDER: S-EPMC8505200 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature