Impact of physiological pacing on functional mitral regurgitation in systolic dysfunction: Initial echocardiographic remodeling findings after His bundle pacing.

ABSTRACT:

Background

Although His bundle pacing (HBP) has been shown to improve left ventricular ejection fraction (LVEF), its impact on mitral regurgitation (MR) remains uncertain.

Objectives

The aim of this study was to evaluate change in functional MR after HBP in patients with left ventricular (LV) systolic dysfunction.

Methods

Paired echocardiograms were retrospectively assessed in patients with reduced LVEF (<50%) undergoing HBP for pacing or resynchronization. The primary outcomes assessed were change in MR, LVEF, LV volumes, and valve geometry pre- and post-HBP. MR reduction was characterized as a decline in ≥1 MR grade post-HBP in patients with ≥grade 3 MR at baseline.

Results

Thirty patients were analyzed: age 68 ± 15 years, 73% male, LVEF 32% ± 10%, 38% corona

SUBMITTER: Upadhyay GA 

PROVIDER: S-EPMC8505206 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature