Impulsive prepotent actions and tics in Tourette disorder underpinned by a common neural network.

ABSTRACT: Tourette disorder (TD), which is characterized by motor and vocal tics, is not in general considered as a product of impulsivity, despite a frequent association with attention deficit hyperactivity disorder and impulse control disorders. It is unclear which type of impulsivity, if any, is intrinsically related to TD and specifically to the severity of tics. The waiting type of motor impulsivity, defined as the difficulty to withhold a specific action, shares some common features with tics. In a large group of adult TD patients compared to healthy controls, we assessed waiting motor impulsivity using a behavioral task, as well as structural and functional underpinnings of waiting impulsivity and tics using multi-modal neuroimaging protocol. We found that unmedicated TD patients showed incre

SUBMITTER: Atkinson-Clement C 

PROVIDER: S-EPMC8505252 | biostudies-literature | 2021 Jul

REPOSITORIES: biostudies-literature