Trajectories of alcohol consumption during life and the risk of developing breast cancer.

ABSTRACT:

Background

Whether there are lifetime points of greater sensitivity to the deleterious effects of alcohol intake on the breasts remains inconclusive.

Objective

To compare the influence of distinctive trajectories of alcohol consumption throughout a woman's life on development of breast cancer (BC).

Methods

1278 confirmed invasive BC cases and matched (by age and residence) controls from the Epi-GEICAM study (Spain) were used. The novel group-based trajectory modelling was used to identify different alcohol consumption trajectories throughout women's lifetime.

Results

Four alcohol trajectories were identified. The first comprised women (45%) with low alcohol consumption (<5 g/day) throughout their life. The second included those (33%) who gradually moved from a

SUBMITTER: Donat-Vargas C 

PROVIDER: S-EPMC8505448 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature