The Impact of Center Volume on Outcomes in Lung Transplantation.

ABSTRACT:

Background

Studies in lung transplantation have shown variable association between hospital volume and clinical outcomes. We aimed to identify the pattern of effect of hospital volume on individual patient survival after lung transplantation.

Methods

We performed a retrospective analysis using the United Network for Organ Sharing national thoracic organ transplantation database. Adult patients who underwent lung transplantation between January 2013 and December 2017 were included. The association between mean annual center volume and 1-year overall survival was examined using restricted cubic splines in a random effects multivariable Cox model. The volume threshold for optimal 1-year overall survival was subsequently approximated by the maximum likelihood approach using segm

SUBMITTER: Yang Z 

PROVIDER: S-EPMC8505551 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature