A millisecond passive micromixer with low flow rate, low sample consumption and easy fabrication.

ABSTRACT: Fast mixing of small volumes of solutions in microfluidic devices is essential for an accurate control and observation of the dynamics of a reaction in biological or chemical studies. It is often, however, a challenging task, as the Reynolds number (Re) in microscopic devices is typically < 100. In this report, we detail a novel mixer based on the "staggered herring bone" (SHB) pattern and "split-recombination" strategies with an optimized geometry, the periodic rotation of the flow structure can be controlled and recombined in a way that the vortices and phase shifts of the flow induce intertwined lamellar structures, thus increasing the contact surface and enhancing mixing. The optimization improves the mixing while using a low flow rate, hence a small volume for mixing and moderate pres

SUBMITTER: Liao Y 

PROVIDER: S-EPMC8505571 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature