Functional connectivity of the anterior insula during withdrawal from cigarette smoking.

ABSTRACT: Currently available therapies for smoking cessation have limited efficacy, and potential treatments that target specific brain regions are under evaluation, with a focus on the insula. The ventral and dorsal anterior subregions of the insula serve distinct functional networks, yet our understanding of how these subregions contribute to smoking behavior is unclear. Resting-state functional connectivity (RSFC) provides a window into network-level function associated with smoking-related internal states. The goal of this study was to determine potentially distinct relationships of ventral and dorsal anterior insula RSFC with cigarette withdrawal after brief abstinence from smoking. Forty-seven participants (24 women; 18-45 years old), who smoked cigarettes daily and were abstinent from smokin

SUBMITTER: Ghahremani DG 

PROVIDER: S-EPMC8505622 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature