The effect of triptorelin and leuprolide on the level of sex hormones in girls with central precocious puberty and its clinical efficacy analysis.

ABSTRACT:

Background

This study aimed to explore the effects of triptorelin and leuprolide on serum hormone levels and the clinical efficacy of girls with idiopathic central precocious puberty (ICPP).

Methods

Retrospective analysis was performed on 128 girls with ICPP who were diagnosed and treated in our hospital from January 2017 to January 2020, including 71 girls in the leuprolide group and 57 girls in the triptorelin group. The differences of serum sex hormone level, ovarian volume, uterine volume, follicle diameter, bone age, growth rate (height change within half a year), maturity (bone age/living age), and other aspects between the two groups of girls were compared.

Results

Before treatment, there was no significant difference in the baseline levels of sex hormones [est

SUBMITTER: Wang L 

PROVIDER: S-EPMC8506057 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature