Diagnostic performance of CT-derived resting distal to aortic pressure ratio (resting Pd/Pa) vs. CT-derived fractional flow reserve (CT-FFR) in coronary lesion severity assessment.

ABSTRACT:

Background

Computed tomography-derived fractional flow reserve (CT-FFR) has emerged as a promising non-invasive substitute for fractional flow reserve (FFR) measurement. Normally, CT-FFR providing functional significance of coronary artery disease (CAD) by using a simplified total coronary resistance index (TCRI) model. Yet the error or discrepancy caused by this simplified model remains unclear.

Methods

A total of 20 consecutive patients with suspected CAD who underwent CTA and invasive FFR measurement were retrospectively analyzed. CT-FFR and CT-(Pd/Pa)_rest values derived from the coronary CTA images. The diagnostic performance of CT-FFR and CT-(Pd/Pa)_rest were evaluated on a per-vessel level using C statistics with invasive FFR<0.80 as the reference s

SUBMITTER: Li Q 

PROVIDER: S-EPMC8506529 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature