Analysis of the expression profile of serum exosomal lncRNA in breast cancer patients.

ABSTRACT:

Background

Breast cancer (BC) is a common tumor that seriously affects women's physical/mental health and even life. BC invasion and metastasis are still the main causes of mortality in BC patients. Exosomal long non-coding RNAs (exo-lncRNA) play an important role in cell communication and can help to understand better the physiological and pathological conditions that result from BC. This study investigates new potential targets and functions of the expression profiles of exo-lncRNAs in BC patients through high-throughput screening and bioinformatics.

Methods

Samples were collected from two BC patients and one healthy subject. The serum exosomal RNAs were subsequently purified, and a library was established for quality inspection and sequencing. The resultant data was compa

SUBMITTER: Zhao X 

PROVIDER: S-EPMC8506548 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature