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ABSTRACT: Background
This study compares standard of care (SOC) open and robotic D2-gastrectomy for locally advanced gastric cancer (LAGC) in the Western context of low disease prevalence, reduced surgical volume, and neoadjuvant chemotherapy (NAC). We hypothesized that robotic gastrectomy (RG) after NAC reduces treatment burden for LAGC across multiple outcome domains vs. SOC.Methods
Single institution, interrupted time series comparing SOC (2008-2013) for LAGC (T2-4Nany/TanyN+) vs. NAC + RG (2013-2018). Treatment burden was a composite metric of narcotic consumption, oncologic efficacy, cumulative morbidity, and 90-day resource utilization. Predictors were evaluated via multivariate modeling. Learning curve analysis was done using CUSUM.Results
After exclusion
SUBMITTER: Rodriguez MJ
PROVIDER: S-EPMC8506707 | biostudies-literature | 2021 Sep
REPOSITORIES: biostudies-literature