Exosomes-a potential indicator and mediator of cleft lip and palate: a narrative review.

ABSTRACT:

Objective

This article summarizes the recent literature on noncoding ribonucleic acids (ncRNAs) in relation to cleft lip with or without palate and exosomes and their usage in craniofacial diseases.

Background

Cleft lip with or without cleft palate (CL/P) is a common congenital malformation with genetic and environmental risk factors that affects numerous children and families. Surgical procedures can correct deformations; however, residual sequelae remain after surgery. Studies exploring the pathogenesis of CL/P are crucial for its early diagnosis and treatment and can inform treatment strategy decisions, etiology searches, and treatment during pregnancy. Recently, research has shown that most disease-related genes are ncRNAs, which are important transcripts in the human tr

SUBMITTER: Chen M 

PROVIDER: S-EPMC8506753 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature