Endothelial Dysfunction as a Component of Severe Acute Respiratory Syndrome Coronavirus 2-Related Multisystem Inflammatory Syndrome in Children With Shock.

ABSTRACT:

Trial registration

NCT04420468.

Objectives

Severe acute respiratory syndrome coronavirus 2-related multisystem inflammatory syndrome in children is frequently associated with shock; endothelial involvement may be one of the underlying mechanisms. We sought to describe endothelial dysfunction during multisystem inflammatory syndrome in children with shock and then assess the relationship between the degree of endothelial involvement and the severity of shock.

Design

Observational study.

Setting

A PICU in a tertiary hospital.

Patients

Patients aged under 18 (n = 28) with severe acute respiratory syndrome coronavirus 2-related multisystem inflammatory syndrome in children and shock, according to the Centers for Disease Control and Prevention criteria.

In

SUBMITTER: Borgel D 

PROVIDER: S-EPMC8507588 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature