Active Flavonoids from Colubrina greggii var. greggii S. Watson against Clinical Isolates of Candida spp.

ABSTRACT: Candida albicans is the most commonly implicated agent in invasive human fungal infections. The disease could be presented as minimal symptomatic candidemia or can be fulminant sepsis. Candidemia is associated with a high rate of mortality and high healthcare and hospitalization costs. The surveillance programs have reported the distribution of other Candida species reflecting the trends and antifungal susceptibilities. Previous studies have demonstrated that C. glabrata more frequently presents fluconazole-resistant strains. Extracts from Mexican plants have been reported with activity against pulmonary mycosis, among them Colubrina greggii. In the present study, extracts from the aerial parts (leaves, flowers, and fruits) of this plant were evaluat

SUBMITTER: Melchor-Martinez EM 

PROVIDER: S-EPMC8510013 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature