Predicting brain function status changes in critically ill patients via Machine learning.

ABSTRACT:

Objective

In intensive care units (ICUs), a patient's brain function status can shift from a state of acute brain dysfunction (ABD) to one that is ABD-free and vice versa, which is challenging to forecast and, in turn, hampers the allocation of hospital resources. We aim to develop a machine learning model to predict next-day brain function status changes.

Materials and methods

Using multicenter prospective adult cohorts involving medical and surgical ICU patients from 2 civilian and 3 Veteran Affairs hospitals, we trained and externally validated a light gradient boosting machine to predict brain function status changes. We compared the performances of the boosting model against state-of-the-art models-an ABD predictive model and its variants. We applied Shapley additive ex

SUBMITTER: Yan C 

PROVIDER: S-EPMC8510304 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature