Graphene Electric Field Sensor Enables Single Shot Label-Free Imaging of Bioelectric Potentials.

ABSTRACT: The measurement of electrical activity across systems of excitable cells underlies current progress in neuroscience, cardiac pharmacology, and neurotechnology. However, bioelectricity spans orders of magnitude in intensity, space, and time, posing substantial technological challenges. The development of methods permitting network-scale recordings with high spatial resolution remains key to studies of electrogenic cells, emergent networks, and bioelectric computation. Here, we demonstrate single-shot and label-free imaging of extracellular potentials with high resolution across a wide field-of-view. The critically coupled waveguide-amplified graphene electric field (CAGE) sensor leverages the field-sensitive optical transitions in graphene to convert electric potentials into the optical reg

SUBMITTER: Balch HB 

PROVIDER: S-EPMC8510444 | biostudies-literature | 2021 Jun

REPOSITORIES: biostudies-literature