Development and evaluation of an indirect ELISA for detection of Teladorsagia circumcincta infection in sheep.

ABSTRACT:

Background

The gastrointestinal helminth, Teladorsagia circumcincta, is one of the major health risks and production-limiting diseases in small ruminant populations, particularly in temperate regions. With the increasing importance of disease management and recruited anthelmintic resistant types, accurate approaches are needed for the diagnosis of the infection in the host. Due to uncertain results using faecal examinations, the ELISA method was indicated for the detection of nematode antigenic materials. Despite some promising results, problems were described in terms of test specificity and cross-reactions. Therefore, this study aimed to evaluate the IgG response to worm somatic and excretory/secretory (ES) products using western blot analysis and an indirect ELISA for the detect

SUBMITTER: Aliabadi J 

PROVIDER: S-EPMC8510574 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature