Sex differences in the behavioral and immune responses of mice to tumor growth and cancer therapy.

ABSTRACT: There is significant variability in the expression of cancer-related fatigue. Understanding the factors that account for this variation provide insight into the underlying mechanisms. One important, but often overlooked, variable is biological sex. While a few clinical studies have indicated that female patients report higher levels of fatigue, these studies are subject to potential socio-culture reporting biases. Only a limited number of preclinical studies have considered sex differences in animal model of fatigue and few have simultaneously considered both disease- and treatment-related factors. The present series of studies was initiated to address the current knowledge gap on the importance of sex differences in cancer-related fatigue. We selected a murine model of human papilloma vir

SUBMITTER: Vichaya EG 

PROVIDER: S-EPMC8511067 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature