Clinical spectrum and the comorbidities of Dravet syndrome in Taiwan and the possible molecular mechanisms.

ABSTRACT: Dravet syndrome (DS) is an uncommon epilepsy syndrome that may negatively affect the patients and their caregivers. However, reliable and valid measures of its impact on caregivers and the characteristics of patients with DS in Taiwan are lacking. This study aimed to describe the characteristics of patients with DS and concerns of their caregivers and establish a baseline frequency of disease characteristics using a cross-sectional survey in Taiwan. We assessed the caregivers of patients with DS using an online anonymous questionnaire. The seizure frequency decreased with age, although lacking statistical significance. Vaccines show no influence on the condition of patients with DS. Our findings revealed the highest impact on the domains affecting the caregivers' daily life, including addi

SUBMITTER: Huang CH 

PROVIDER: S-EPMC8511137 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature