Effects of Patient and Surgery Characteristics on Persistent Postoperative Pain: A Mediation Analysis.

ABSTRACT:

Objective

Acute postoperative pain intensity is associated with persistent postsurgical pain (PPP) risk. However, it remains unclear whether acute postoperative pain intensity mediates the relationship between clinical factors and persistent pain.

Materials and methods

Participants from a mixed surgical population completed the Brief Pain Inventory and Pain Catastrophizing Scale before surgery, and the Brief Pain Inventory daily after surgery for 7 days and at 30 and 90 days after surgery. We considered mediation models using the mean of the worst pain intensities collected daily on each of postoperative days (PODs) 1 to 7 against outcomes of worst pain intensity at the surgical site endpoints reflecting PPP (POD 90) and subacute pain (POD 30).

Results

The analyzed co

SUBMITTER: Mi X 

PROVIDER: S-EPMC8511273 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature