Acute White Matter Integrity Post-trauma and Prospective Posttraumatic Stress Disorder Symptoms.

ABSTRACT: Background: Little is known about what distinguishes those who are resilient after trauma from those at risk for developing posttraumatic stress disorder (PTSD). Previous work indicates white matter integrity may be a useful biomarker in predicting PTSD. Research has shown changes in the integrity of three white matter tracts-the cingulum bundle, corpus callosum (CC), and uncinate fasciculus (UNC)-in the aftermath of trauma relate to PTSD symptoms. However, few have examined the predictive utility of white matter integrity in the acute aftermath of trauma to predict prospective PTSD symptom severity in a mixed traumatic injury sample. Method: Thus, the current study investigated acute brain structural integrity in 148 individuals being treated for traumatic inju

SUBMITTER: Weis CN 

PROVIDER: S-EPMC8511512 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature