Validation of the Applied Biosystems RapidHIT ID instrument and ACE GlobalFiler Express sample cartridge.

ABSTRACT: Rapid DNA platforms are fully automated systems capable of processing DNA from biological samples and interpreting the results in approximately 90 minutes with minimal human intervention. With a greater reliance on the system than on the analyst, validation data are especially needed to define the performance and limitations of commercially available Rapid DNA systems. Thus, validation studies of a Rapid DNA workflow consisting of the Applied Biosystems RapidHIT ID Instrument and RapidLINK software with a focus on the ACE GlobalFiler Express Sample Cartridge and reference buccal swabs were performed in accordance with Scientific Working Group on DNA Analysis Methods Validation Guidelines. These validation studies included assessments of sensitivity, contamination, concordance, reproducibil

SUBMITTER: Cihlar JC 

PROVIDER: S-EPMC8511620 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature