Utilization of a Wheat Sidestream for 5-Aminovalerate Production in Corynebacterium glutamicum.

ABSTRACT: Production of plastics from petroleum-based raw materials extensively contributes to global pollution and CO₂ emissions. Biotechnological production of functionalized monomers can reduce the environmental impact, in particular when using industrial sidestreams as feedstocks. Corynebacterium glutamicum, which is used in the million-ton-scale amino acid production, has been engineered for sustainable production of polyamide monomers. In this study, wheat sidestream concentrate (WSC) from industrial starch production was utilized for production of l-lysine-derived bifunctional monomers using metabolically engineered C. glutamicum strains. Growth of C. glutamicum on WSC was observed and could be improved by hydrolysis of WSC. By heterologous expression of the ge

SUBMITTER: Burgardt A 

PROVIDER: S-EPMC8511785 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature