Development of Amino Acids Functionalized SBA-15 for the Improvement of Protein Adsorption.

ABSTRACT: Ordered mesoporous materials and their modification with multiple functional groups are of wide scientific interest for many applications involving interaction with biological systems and biomolecules (e.g., catalysis, separation, sensor design, nano-science or drug delivery). In particular, the immobilization of enzymes onto solid supports is highly attractive for industry and synthetic chemistry, as it allows the development of stable and cheap biocatalysts. In this context, we developed novel silylated amino acid derivatives (Si-AA-NH2) that have been immobilized onto SBA-15 materials in biocompatible conditions avoiding the use of toxic catalyst, solvents or reagents. The resulting amino acid-functionalized materials (SBA-15@AA) were characterized by XRD, TGA, EA, Zeta potential, nitro

SUBMITTER: Gutierrez-Climente R 

PROVIDER: S-EPMC8512485 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature