Nickel-Catalyzed Kumada Cross-Coupling Reactions of Benzylic Sulfonamides.

ABSTRACT: Herein, we report a Kumada cross-coupling reaction of benzylic sulfonamides. The scope of the transformation includes acyclic and cyclic sulfonamide precursors that cleanly produce highly substituted acyclic fragments. Preliminary data are consistent with a stereospecific mechanism that allows for a diastereoselective reaction.

SUBMITTER: Hewitt KA 

PROVIDER: S-EPMC8512530 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature