Lipidomic profiling reveals distinct differences in plasma lipid composition in overweight or obese adolescent students.

ABSTRACT:

Introduction

The relationship between dyslipidemia and obesity has been widely reported, but the global lipid profiles associated with the development of obesity still need to be clarified. An investigation into the association between the lipidomic plasma profile and adolescent obesity may provide new insights into the development of obesity.

Methods

Mass spectrometry coupled with liquid chromatography was applied to detect the global lipidome in the fasting plasma from 90 Chinese adolescents, including 34 obese adolescents, 26 overweight adolescents, and 30 adolescents with a normal body mass index (BMI). All participants underwent anthropometric measurements by using InBody. Clinical biochemical indicators were measured by Cobas Elecsys.

Results

Both qualitative an

SUBMITTER: Yin R 

PROVIDER: S-EPMC8513241 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature