The Indirect Antiviral Potential of Long Noncoding RNAs Encoded by IFITM Pseudogenes.
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ABSTRACT:
SUBMITTER: Rahman K
PROVIDER: S-EPMC8513482 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Publications
The Indirect Antiviral Potential of Long Noncoding RNAs Encoded by IFITM Pseudogenes.
Rahman Kazi K Compton Alex A AA
Journal of virology 20210728 21
The interferon-induced transmembrane (<i>IFITM</i>) gene family performs multiple functions in immunity, including inhibition of virus entry into cells. The <i>IFITM</i> repertoire varies widely between species and consists of protein-coding genes and pseudogenes. The selective forces driving pseudogenization within gene families are rarely understood. In this issue, the human pseudogene <i>IFITM4P</i> is characterized as a virus-induced, long noncoding RNA that contributes to restriction of inf ...[more]
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