Safety and efficacy of very low carbohydrate diet in patients with diabetic kidney disease-A randomized controlled trial.

ABSTRACT:

Introduction

There is limited data on the effects of low carbohydrate diets on renal outcomes particularly in patients with underlying diabetic kidney disease. Therefore, this study determined the safety and effects of very low carbohydrate (VLCBD) in addition to low protein diet (LPD) on renal outcomes, anthropometric, metabolic and inflammatory parameters in patients with T2DM and underlying mild to moderate kidney disease (DKD).

Materials and methods

This was an investigator-initiated, single-center, randomized, controlled, clinical trial in patients with T2DM and DKD, comparing 12-weeks of low carbohydrate diet (<20g daily intake) versus standard low protein (0.8g/kg/day) and low salt diet. Patients in the VLCBD group underwent 2-weekly monitoring including their 3-day f

SUBMITTER: Zainordin NA 

PROVIDER: S-EPMC8513884 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature