Modulation of neural activity in frontopolar cortex drives reward-based motor learning.

ABSTRACT: The frontopolar cortex (FPC) contributes to tracking the reward of alternative choices during decision making, as well as their reliability. Whether this FPC function extends to reward gradients associated with continuous movements during motor learning remains unknown. We used anodal transcranial direct current stimulation (tDCS) over the right FPC to investigate its role in reward-based motor learning. Nineteen healthy human participants practiced novel sequences of finger movements on a digital piano with corresponding auditory feedback. Their aim was to use trialwise reward feedback to discover a hidden performance goal along a continuous dimension: timing. We additionally modulated the contralateral motor cortex (left M1) activity, and included a control sham stimulation. Right FPC-tD

SUBMITTER: Herrojo Ruiz M 

PROVIDER: S-EPMC8514446 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature