Slow deep breathing modulates cardiac vagal activity but does not affect peripheral glucose metabolism in healthy men.

ABSTRACT: Parasympathetic nervous system innervates peripheral organs including pancreas, hepatic portal system, and gastrointestinal tract. It thereby contributes to the regulation of whole-body glucose metabolism especially in the postprandial state when it promotes secretion of insulin and enhances its action in major target organs. We now aimed to evaluate the effect of parasympathetic modulation on human glucose metabolism. We used slow deep breathing maneuvers to activate the parasympathetic nervous system and tested for effects on metabolism during an oral glucose tolerance test in a randomized, controlled, cross-over trial in 15 healthy young men. We used projections towards the heart as a readout for parasympathetic activity. When analyzing heart rate variability, there was a significant in

SUBMITTER: Vosseler A 

PROVIDER: S-EPMC8514507 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature