Genomic Insight Into the Population Admixture History of Tungusic-Speaking Manchu People in Northeast China.

ABSTRACT: Manchu is the third-largest ethnic minority in China and has the largest population size among the Tungusic-speaking groups. However, the genetic origin and admixture history of the Manchu people are far from clear due to the sparse sampling and a limited number of markers genotyped. Here, we provided the first batch of genome-wide data of genotyping approximate 700,000 single-nucleotide polymorphisms (SNPs) in 93 Manchu individuals collected from northeast China. We merged the newly generated data with data of publicly available modern and ancient East Asians to comprehensively characterize the genetic diversity and fine-scale population structure, as well as explore the genetic origin and admixture history of northern Chinese Manchus. We applied both descriptive methods of ADMIXTURE, fin

SUBMITTER: Zhang X 

PROVIDER: S-EPMC8515022 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature