Adverse drug reactions of leukotriene receptor antagonists in children with asthma: a systematic review.

ABSTRACT:

Background

Asthma is the most common chronic condition of childhood. Leukotriene receptor antagonists (LTRAs) are included in international guidelines for children and young people (CYP), but there have been highly publicised concerns about potential adverse effects. The aim was to identify and understand the reported frequency of adverse drug reactions (ADRs) attributed to LTRAs in CYP with asthma.

Methods

Embase, MEDLINE, PubMed and CINAHL were searched up to October 2020. Reference lists of eligible papers were manually screened. Eligible studies identified adverse events attributed to an LTRA in individuals aged between 0 and 18 years diagnosed with asthma. Four different tools were used to assess risk of bias or quality of data to accommodate the papers assessed.

Res

SUBMITTER: Dixon EG 

PROVIDER: S-EPMC8515462 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature