Metal-Organic Framework-Stabilized High Internal Phase Pickering Emulsions Based on Computer Simulation for Curcumin Encapsulation: Comprehensive Characterization and Stability Mechanism.

ABSTRACT: High internal phase Pickering emulsions (HIPPEs) have taken a center stage in the arena of delivery systems in the food industry because of their high loading capacity and stability. In addition, metal-organic frameworks (MOFs), a type of cutting-edge designable porous scaffolding material, have attracted attention in reticular chemistry, which satisfies fundamental demands for delivery research in the past years. Here, we demonstrate a novel metal-organic framework (MOF)-stabilized HIPPE delivery system for hydrophobic phytochemicals. First, a novel high-biocompatibility and stable MOF particle, UiO-66-NH₂, was selected from atomic simulation screening, which showed proper electronegativity and amphiphilic properties to develop the HIPPE system. Monodispersed UiO-66-NH₂

SUBMITTER: Ma P 

PROVIDER: S-EPMC8515605 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature