Persistent eosinopenia is associated with in-hospital mortality among older patients: unexpected prognostic value of a revisited biomarker.

ABSTRACT:

Introduction

Infection is one of the major causes of mortality and morbidity in older adults. Available biomarkers are not associated with prognosis in older patients. This study aimed to analyze the value of eosinopenia (eosinophil count< 100/mm³) as a prognosis marker among older patients with suspected or confirmed bacterial infection.

Methods

A retrospective study was performed from 1 January to 31 December 2018 among patients in a geriatrics ward suffering from a bacterial infection treated with antibiotics. Biomarker data including the eosinophil count, neutrophil count and C-reactive protein (CRP) were collected within 4 days after patient diagnosis. Persistent eosinopenia was defined as a consistent eosinophil count< 100/mm³ between Day 2 and Da

SUBMITTER: Partouche B 

PROVIDER: S-EPMC8516088 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature