Ontology highlight
ABSTRACT:
SUBMITTER: Keller TCS
PROVIDER: S-EPMC8516448 | biostudies-literature | 2021 Oct
REPOSITORIES: biostudies-literature
Keller T C Stevenson TCS Lim Lillian L Shewale Swapnil V SV McDaid Kendra K Martí-Pàmies Íngrid Í Tang Alan T AT Wittig Carl C Guerrero Andrea A AA Sterling Stephanie S Leu N Adrian NA Scherrer-Crosbie Marielle M Gimotty Phyllis A PA Kahn Mark L ML
The Journal of clinical investigation 20211001 20
In recent decades, treatments for myocardial infarction (MI), such as stem and progenitor cell therapy, have attracted considerable scientific and clinical attention but failed to improve patient outcomes. These efforts indicate that more rigorous mechanistic and functional testing of potential MI therapies is required. Recent studies have suggested that augmenting post-MI lymphatic growth via VEGF-C administration improves cardiac function. However, the mechanisms underlying this proposed thera ...[more]