Responsiveness Index versus the RASS-Based Method for Adjusting Sedation in Critically Ill Patients.

ABSTRACT:

Background

Sedation of intensive care patients is needed for patient safety, but deep sedation is associated with adverse outcomes. Frontal electromyogram-based Responsiveness Index (RI) aims to quantify the level of sedation and is scaled 0-100 (low index indicates deep sedation). We compared RI-based sedation to Richmond Agitation-Sedation Scale- (RASS-) based sedation. Our hypothesis was that RI-controlled sedation would be associated with increased total time alive without mechanical ventilation at 30 days without an increased number of adverse events.

Methods

32 critically ill adult patients with mechanical ventilation and administration of sedation were randomized to either RI- or RASS-guided sedation. Patients received propofol and oxycodone, if possible. The followin

SUBMITTER: Wennervirta JE 

PROVIDER: S-EPMC8516552 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature