Optic Nerve Head Hemoglobin Levels in Glaucoma: A Structural and Functional Correlation Study.

ABSTRACT:

Purpose

To investigate structural and functional correlations in glaucoma patients using optic nerve head hemoglobin (ONH Hb) measurements as determined by automated colorimetric analysis of conventional retinography.

Methods

We prospectively enrolled healthy participants and glaucomatous patients with a wide range of disease stages. All participants underwent visual field (VF) testing (standard automated perimetry, SAP), color fundus imaging (mydriatic retinography), and peripapillary retinal nerve fiber layer (pRNFL) assessment through spectral-domain optical coherence tomography (SD-OCT). Software Laguna ONhE was used to estimate the amount of ONH Hb and to determine the glaucoma discriminant function (GDF) index. Scatter plots were constructed, and regression analysis wa

SUBMITTER: Rocha JAG 

PROVIDER: S-EPMC8516580 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature