Life-Threatening Bleeding in Children: A Prospective Observational Study.

ABSTRACT:

Objectives

The purpose of our study was to describe children with life-threatening bleeding.

Design

We conducted a prospective observational study of children with life-threatening bleeding events.

Setting

Twenty-four childrens hospitals in the United States, Canada, and Italy participated.

Subjects

Children 0-17 years old who received greater than 40 mL/kg total blood products over 6 hours or were transfused under massive transfusion protocol were included.

Interventions

Children were compared according bleeding etiology: trauma, operative, or medical.

Measurements and main results

Patient characteristics, therapies administered, and clinical outcomes were analyzed. Among 449 enrolled children, 55.0% were male, and the median age was 7.3 years. B

SUBMITTER: Leonard JC 

PROVIDER: S-EPMC8516672 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature