Impact of smoking Behavior on cognitive functioning in persons at risk for psychosis and healthy controls: A longitudinal study.

ABSTRACT:

Background

The high prevalence of smoking in individuals who are at ultra-high risk (UHR) for psychosis is well known and moderate cognitive deficits have also been found in UHR. However, the association between smoking and cognition in UHR is unknown and longitudinal studies are lacking.

Method

A cohort study with 330 UHR individuals and 66 controls was conducted, as part of the European network of national schizophrenia networks studying gene-environment interactions (EU-GEI). At baseline and after 6, 12, and 24 months, smoking behavior was assessed with the Composite International Diagnostic Interview and cognitive functioning with a comprehensive test battery. Linear mixed-effects analyses were used to examine the multicross-sectional and prospective associations between

SUBMITTER: van der Heijden HS 

PROVIDER: S-EPMC8516743 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature