Ontology highlight
ABSTRACT:
SUBMITTER: Haga SB
PROVIDER: S-EPMC8517135 | biostudies-literature | 2021
REPOSITORIES: biostudies-literature
Frontiers in genetics 20211001
Incidental or secondary findings have been a major part of the discussion of genomic medicine research and clinical applications. For pharmacogenetic (PGx) testing, secondary findings arise due to the pleiotropic effects of pharmacogenes, often related to their endogenous functions. Unlike the guidelines that have been developed for whole exome or genome sequencing applications for management of secondary findings (though slightly different from PGx testing in that these refer to detection of va ...[more]