Association of sarcopenia with incident osteoporosis: a prospective study of 168,682 UK biobank participants.

ABSTRACT:

Background

Sarcopenia often co-occurs with osteoporosis in cross-sectional studies. However, this association has rarely been studied in prospective studies. This study aimed to investigate the association between sarcopenia categories-along with its individual components-and incident osteoporosis in both middle-aged and older men and women from the UK Biobank study.

Methods

A total of 168,682 participants (48.8% women, aged 37 to 70 years at baseline) were included in this prospective study. Categories of sarcopenia (pre-sarcopenia and sarcopenia), and its individual components, were defined according to the EWGSOP2 criteria (2019). Associations with incident osteoporosis by sex were investigated using Cox-proportional hazard models adjusted for socio-demographic, lifestyle

SUBMITTER: Petermann-Rocha F 

PROVIDER: S-EPMC8517357 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature