Fecal Bile Acids Profile of Crewmembers Consuming the Same Space Food in a Spacecraft Simulator.

ABSTRACT: Introduction: Recently, bile acids (BAs) are increasingly being considered as unique metabolic integrators and not just for the cholesterol metabolism and absorption of dietary lipids. Human BAs profiles are evolved to be individual under different environmental, dietary, and inherited factors. Variation of BAs for crewmembers from freshly prepared kitchen diets to wholly prepackaged industrial foods in a ground-based spacecraft simulator has not been clearly interpreted. Methods: Three crewmembers were confined in a docked spacecraft and supplied with 7 days periodic wholly prepackaged industrial foods for 50 days. Fecal samples were collected before entry in the spacecraft simulator and after evacuation. Determination of 16 kinds of BAs was carried out by high-performance l

SUBMITTER: Dong HS 

PROVIDER: S-EPMC8517451 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature