First Report of bla _IMP-4 and bla _SRT-2 Coproducing Serratia marcescens Clinical Isolate in China.

ABSTRACT: Carbapenem-resistant Enterobacterales (CRE) has become a major therapeutic concern in clinical settings, and carbapenemase genes have been widely reported in various bacteria. In Serratia marcescens, class A group carbapenemases including SME and KPC were mostly identified. However, there are few reports of metallo-β-lactamase-producing S. marcescens. Here, we isolated a carbapenem-resistant S. marcescens (S378) from a patient with asymptomatic urinary tract infection which was then identified as an IMP-4-producing S. marcescens at a tertiary hospital in Sichuan Province in southwest of China. The species were identified using MALDI-TOF MS, and carbapenemase-encoding genes were detected using PCR and DNA sequencing. The results of antimicrobial susceptibi

SUBMITTER: Huang X 

PROVIDER: S-EPMC8517538 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature